Welcome to the NINDS Ideascale Community

NINDS wants to hear your ideas! Use this site to submit your ideas, add comments, and share your expertise on NINDS projects. We hope to hear from people from all backgrounds and perspectives to spur innovation and support our mission to reduce the burden of neurological disease. Explore the individual campaigns to see how YOU can contribute today!

Show Us Your BRAINs! Photo & Video Contest

Thinking about a Greener Future trending idea

Mouse brain showing green AAV-transduced cells in the cortex and hippocampus. Neurons are labeled red and nuclei are blue.

Show Us Your BRAINs! Photo & Video Contest

Model of mouse V1 with a Neuropixels probe trending idea

This rendering of a model of mouse primary visual cortex with a Neuropixels probe was created using a new tool, VND (Visual Neuronal Dynamics).

Full name Barry Isralewitz, John Stone, Mariano Spivak, Kael Dai, Josh Siegle, Emad Tajkhorshid, and Anton Arkhipov

Submission Type Photo

Institution or organization University of Illinois at Urbana-Champaign and Allen Institute

Show Us Your BRAINs! Photo & Video Contest

DBS lead placement for OCD trending idea

360 degree view of deep brain stimulation (DBS) lead placement in one participant that underwent DBS surgery for obsessive compulsive disorder (OCD).

Full name Nicole Provenza, Raissa Mathura, Noam Peled, Evan Dastin-van Rijn, Kelly Bijanki, Sameer Sheth, David Borton, Wayne Goodman

Submission Type Video

Institution or organization Brown University, Baylor College of Medicine

Show Us Your BRAINs! Photo & Video Contest

Neuron on Fire trending idea

Hippocampal CA1 pyramidal neuron in the mouse, recorded from the distal dendrite using patch clamp electrophysiology. The recorded location is visible as the gap in the dendrite. The neuron was filled with biocytin during recording and immunostained with streptavidin-647 post hoc. Confocal image was filtered using ImageJ.

Full name Olesia Bilash

Submission Type Photo

Institution or organization New York University

Show Us Your BRAINs! Photo & Video Contest

Non-invasive in vivo mapping of the human amygdala circuit trending idea

Tractography of three critical amygdala pathways: the ventral amygdalofugal pathway, the stria terminalis and the amygdala-prefrontal pathway.

Full name Josue Avecillas-Chasin, Ausaf Bari, Jean-Philippe Langevin

Submission Type Video

Institution or organization UCLA

Show Us Your BRAINs! Photo & Video Contest

THC Exposure visualized the cerebral cortex trending idea

The endocannabinoid system serves a critical role in homeostatic regulation through its influence on processes underlying appetite, pain, reward, and stress, and cannabis has long been used for the related modulatory effects it provides through tetrahydrocannabinol (THC).

We investigated how THC exposure relates to tissue microstructure of the cerebral cortex and subcortical nuclei using computational modeling of diffusion... more »

Submission Type Video

Show Us Your BRAINs! Photo & Video Contest

Pyramidal tract reconstruction in vivo trending idea

Pyramidal tract of an HCP subject reconstructed in vivo using Radial DSI and ODF-Fingerprinting. Improved reconstruction of fibers crossing at shallow angles ensured by ODF-Fingerprinting allowed to reproduce the reach fanning shape of cortical terminations of the tract. Images were rendered in DSI Studio.

Full name Patryk Filipiak

Submission Type Video

Institution or organization NYU School of Medicine

Show Us Your BRAINs! Photo & Video Contest

Super-resolved dendrites in visual cortical circuits trending idea

3D super-resolution image of immunofluorescence-labeled ChR2–EYFP on dendrites in 50-μm-thick brain section of visual cortical circuits.

Submission Type Photo

Show Us Your BRAINs! Photo & Video Contest

Emergence of the Largest Central Mammalian Nerve Terminal trending idea

Lattice light sheet microscopy reveals presynaptic collateral dynamics in the developing calyx of Held during the first week of life in the auditory brainstem of the mouse.

Show Us Your BRAINs! Photo & Video Contest

Ajrak Print on the Corticospinal Tract (CST) Left trending idea

This is Sindhi Ajrak print digitally painted on the Corticospinal Tract (CST) Left. Ajrak print is 3000 years old unique form of block-printing found in Sindh, Pakistan. Ajrak print is mostly hand-painted on shawls made using block printing by stamps. Ajrak has become a symbol of the Sindhi culture and traditions. Using my programming skills, I painted Ajrak on my favorite white matter tract, CST.

Show Us Your BRAINs! Photo & Video Contest

Human brain perivascular spaces

3D rendered image of segmented Perivascular Spaces (PVSs), superimposed on a high-resolution 7 Tesla anatomical MRI of a healthy adult brain. PVSs, also known as Virchow-Robin spaces, are fluid-filled structures that accompany vessels entering (penetrating arteries) or leaving (draining veins) the cerebral cortex. Mapping PVSs has significant clinical value because it plays a key role in the circulation of the cerebrospinal... more »

Show Us Your BRAINs! Photo & Video Contest

Microvessels Fairylights

Isolated cerebral microvessels from transgenic sickle mouse. Immunofluorescence staining with red (CD31, endothelial cell marker) and green (Aquaporin-4, astrocyte marker), counterstained with sparkling blue (DAPI, nuclei detector).

Submission Type Photo

Show Us Your BRAINs! Photo & Video Contest

Reconstructed Mouse Cervical Spinal Cord

Serially sectioned spinal cord with marked coordinates of V1-Interneurons and cells infected by neuronal tracer pseudorabies virus - 3D reconstructed.

Full name Jamie Anne Mortel

Submission Type Video

Institution or organization Salk Institute for Biological Studies