2020 Epilepsy Research Benchmarks

Benchmark Area II

Benchmark 2 – Prevent epilepsy and its progression.

• Grand Challenge idea: "Biomarkers for Prevention before Seizure Onset" – Following the example of TSC and vigabatrin, a grand challenge may be to identify the range of other epilepsies that can be accurately identified before seizures emerge, and develop targeted programs to develop biomarkers and preventive treatments. Examples could include individuals with higher risk of epilepsy associated with HIE, autism, depression, stoke or TBI. Consider genetic epilepsies that could be identified through prenatal or newborn screening or other comorbidity that emerges before seizures.

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Idea No. 219